Table 1.
Discovery cohort | Validation cohort | Validation cohort | |||
---|---|---|---|---|---|
TCGA (n = 355) | GSE39582 (n = 557) | GSE41258 (n = 185 | |||
Characteristic | n (%) | Characteristic | n (%) | Characteristic | n (%) |
Age at diagnosis | Age at diagnosis | Age at diagnosis | |||
Mean (SD) | 64.5 (13.3) | Mean (SD) | 66.8 (13.3) | Mean (SD) | 63.5 (14.0) |
AJCC TNM stage | AJCC TNM stage | AJCC TNM stage | |||
I | 56 (15.8) | I | 31 (5.6) | I | 28 (15.1) |
II | 135 (38.0) | II | 262 (47.0) | II | 50 (27.0) |
III | 112 (31.5) | III | 204 (36.6) | III | 49 (26.5) |
IV | 52 (14.7) | IV | 60 (10.8) | IV | 58 (31.4) |
Survival event | Survival event | Survival event | |||
Dead | 78 (22.0) | Dead | 190 (34.1) | Dead | 102 (55.1) |
Alive | 277 (78.0) | Alive | 367 (65.9) | Alive | 83 (44.9) |
Median follow-up time, months (range) | Median follow-up time, months (range) | Median follow-up time, months (range) | |||
22 (0–148) | 52 (0–201) | 66 (0–203) | |||
Median time to survival event, months (range) | Median time to survival event, months (range) | Median time to survival event, months (range) | |||
17 (1–100) | 31 (0–183) | 34 (0–196) |
TCGA: The cancer genome atlas; GEO: gene expression omnibus; SD: standard deviation; AJCC: American Joint Committee on Cancer.