Fig. 8.

Effect of LINC01234, SHMT2 and miR-642a-5p on tumor growth in vivo. a Tumors formed in nude mice. LoVo cells and HCT116 cells stably transfected with negative control (NC), sh-LINC01234, sh-SHMT2 or miR-642a-5p-expressing vectors were injected into the flanks of nude mice (n = 5), and the mice were sacrificed after 4 weeks. b Images of whole tumors from the nude mice injected with LoVo cells and HCT116 cells stably transfected with negative controls (NC), sh-LINC01234, sh-SHMT2 or miR-642a-5p-expressing vector. c The average volume and weight of the tumors from the mice injected with LoVo cells and HCT116 cells stably transfected with sh-LINC01234, sh-SHMT2 or miR-642a-5p-expressing vector were significantly lower than those injected with negative control cells. The data are expressed as the mean ± sd. *P < 0.05