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. 2019 Feb 12;10(2):136. doi: 10.1038/s41419-019-1355-1

Fig. 1. High HMGB1 expression associates with recurrence and poor outcome after postoperative radiotherapy in locally advanced resected ESCC.

Fig. 1

a Representative images of immunohistochemical (IHC) staining of HMGB1 protein in clinical ESCC samples. R, recurrence; NR, non-recurrence. b Tumor expression of HMGB1 and recurrence rate in clinical ESCC samples, Chi-square test. c Immunoreactivity score (IRS) of HMGB1 protein in clinical ESCC samples, unpaired Mann–Whitney U test. d Kaplan-Meier analyses of RFS for ESCC with high- or low-level tumor expression of HMGB1, Log-rank test