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. 2018 Nov 27;44(4):817–825. doi: 10.1038/s41386-018-0282-7

Fig. 1.

Fig. 1

Histology and set-shift procedure. a Microphotograph of Cresyl violet stained coronal section containing guide canulae tracks for injections directly in the prefrontal cortex (PFC). b Schematic representation of the injection sites (circles) superimposed on the coronal plane of a rat brain (modified from [25]). Numbers on the schemes indicate distance from Bregma point. c Experimental timeline for the attentional set-shift procedure. The grey rectangles represent front panel of the operant box, circles correspond to the light cues (gray = light off; white = light on), white rectangles correspond to extended levers, the lever rewarded with sucrose pellet is indicated with plus sign above it; D1-D4 indicate different days of the procedure. Note that rats were injected with the drug solution on the last day of the procedure