Fig. 3.

Effects of quercetin on the phosphorylation signal related to muscle atrophy in C2C12 cells.

Cells were treated with DEX for 4 h after 24 h in the presence or absence of quercetin treatment. (A) Graphs express the relative gene expression of atrogin-1 and MuRF-1. Values represent the mean ± SE (n = 5–6). (B) Graphs express the relative protein expression of p-Smad2/Smad2, p-Foxo3a/Foxo3a and p-Akt/Akt. Values represent the mean ± SE (n = 4). Significant differences were determined by Dunnett's test (*p < 0.05).