2.

Multivariate analysis of predictive factors associated with overall survival (OS) and disease-free survival (DFS)

Variables	OS				DFS
	β	HR (95%CI)	P		β	HR (95%CI)	P
β, the coefficients in the COX regression; HR, hazard ratio; CI, confidence interval; MVI, macroscopic vascular invasion; TBIL, total bilirubin; AFP, α-fetoprotein; ALP, alkaline phosphatase; BT, blood transfusion; AST, aspartate aminotransferase.
Tumor size (cm)			0.015				0.005
5–10/<5	0.789	2.200 (1.185–4.085)	0.013		0.576	1.779 (1.019–3.104)	0.043
≥ 10/<5	0.950	2.586 (1.346–4.968)	0.004		1.002	2.724 (1.490–4.981)	0.001
MVI
Yes/no	0.509	1.664 (0.962–2.879)	0.069		0.508	1.129 (0.729–1.750)	0.587
TBIL (μmol/L)
> 17.1/≤ 17.1	0.238	1.269 (0.808–1.991)	0.301		0.191	1.211 (0.789–1.859)	0.382
AFP (ng/mL)			0.003				0.008
20–400/≤ 20	0.576	1.779 (0.782–4.048)	0.170		0.491	1.633 (0.758–3.518)	0.210
> 400/≤ 20	0.967	2.629 (1.495–4.624)	0.001		0.794	2.212 (1.337–3.659)	0.002
ALP (U/L)
> 100.5/≤ 100.5	0.560	1.751 (1.070–2.865)	0.026		0.559	1.749 (1.074–2.848)	0.025
BT in hospital
Yes/no	0.157	1.170 (0.748–1.831)	0.491		0.121	1.129 (0.729–1.750)	0.587
AST (U/L)
> 40/≤ 40					0.097	0.907 (0.579–1.422)	0.672