Methods |
Setting: clinic, USA Recruitment: media adverts and referral |
Participants |
135 smokers; 59% female, average age approximately 36, average cigs/day 29 Therapists: 2 psychologists, randomly assigned to groups |
Interventions |
2 × 2 factorial trial, aversive smoking conditions collapsed 1. Skills training, 14 × 75 minute sessions. 8 sessions over 3 weeks involved 6 seconds or 30 seconds of aversive smoking. 6 sessions over week 1 to 6 covered relaxation, commitment and cost benefits, and relapse prevention skills with role‐play of risk situations 2. Discussion control. Same aversive smoking. Other 6 sessions used self‐scoring tests and group discussion. Discussion of specific skills discouraged |
Outcomes |
Abstinence at 12 months (point prevalence) Validation: CO < 10 ppm, plasma thiocyanate < 85 ng/mg and confirmation from significant other |
Notes |
Matched for contact time Author tested for therapist and cohort main effects. None significant |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Randomisation method not described |
Allocation concealment (selection bias) |
Unclear risk |
No details given |
Blinding of participants and personnel (performance bias) All outcomes |
Unclear risk |
No details given |
Blinding of outcome assessment (detection bias) All outcomes |
Low risk |
Biochemical validation used |
Incomplete outcome data (attrition bias) All outcomes |
Low risk |
8 dropouts from group 1 and 4 from group 2 before start of relapse prevention sessions reincluded in this analysis |