Table 1.
Upregulation secretory factors in 4T1 tumors in the lungs of mice
| Gene | Folds | Gene | Folds | Gene | Folds | Gene | Folds |
|---|---|---|---|---|---|---|---|
| CCL1 | 2.468 | CXCL15 | 38.937 | FGF4 | 19.932 | HGF | 8.082 |
| CCL4 | 2.028 | CXCL17 | 24.092 | FGF10 | 9.988 | VEGF | 7.924 |
| CCL5 | 4.030 | CXCL12 | 9.338 | FGF1 | 7.007 | ET-1 | 6.417 |
| IL33 | 3.619 | CXCL10 | 4.05 | FGF18 | 4.833 | IGF1 | 2.990 |
| IL12 | 3.561 | CXCL9 | 3.279 | GDF5 | 9.746 | TGFb2 | 3.768 |
| IL17r | 2.283 | MMP7 | 3.222 | GDF15 | 7.745 | LTF | 10.370 |
| WNT4 | 2.696 | MMP8 | 8.501 | TNF | 3.612 | PDGFB | 2.401 |
| WNT6 | 8.163 | MMP15 | 3.519 | TNFSF10 | 3.424 | ||
| WNT10A | 3.788 | TNFSF13B | 3.102 |
4T1 cells were implanted into the mammary fat pads and allowed to spontaneously spread to the lung for 24 days. Whole primary tumor in mammary and tumor nodules in lungs (tumor nodules = 8) were subjected to microarray