Table 1.
Overview of assessments
Measure | Assessment | T0 | T1 | T2 | T3 | T4 | T5 | T6 | Treat-ments |
---|---|---|---|---|---|---|---|---|---|
SCID | Diagnosis | x | |||||||
General patient characteristics | Demographic information | x | |||||||
Clinical background | Therapy history | x | |||||||
CTQ | Childhood trauma | x | |||||||
AQ | Autism quotient | x | |||||||
FQ | Presence and severity phobic symptoms | x | x | x | x | x | x | ||
BAI | Anxiety severity | x | x | x | x | x | x | ||
CGI | Clinical global impression | x | |||||||
SUDS | Degree of habituation and extinction | x | |||||||
BDI | Depression | x | x | x | x | x | |||
BSQ | Somatic symptoms | x | x | x | x | x | |||
EQ5D | Quality of life | x | x | x | x | x | |||
Tic-P | Loss of work and productivity plus health care costs | x | x | x | x | x | |||
SPAI | Social phobia and anxiety severity | x | x | x | x | x | |||
LSAS | Social anxiety severity (SOC PHOB) | x | x | x | x | x | |||
PDSS | Panic disorder severity (PD + AGO) | x | x | x | x | x | |||
MI | Mobility inventory (PD + AGO) | x | x | x | x | x | |||
ACQ | Agoraphobia severity (PD + AGO) | x | x | x | x | x | |||
Fear conditioning task | Acquisition and extinction of fear learning | x | x | x | |||||
Blood | CBD level, DNA, epigenetics | x | x |
Questionnaires that are only assessed for a specific diagnosis are specified between brackets (panic disorder with agoraphobia = PD + AGO, social phobia = SOC PHOB). T0 = Baseline, T1 = First medication administration, T2 = Mid treatment, T3 = Last medication administration, T4 = Post treatment, T5 = Follow up (3 months), T6 = Follow up (6 months), Treatments = All 8 therapy sessions. SCID Structured Clinical Interview for DSM disorders axis I, CTQ Childhood Trauma Questionnaire, AQ Autism spectrum Quotient, FQ Fear Questionnaire, BAI Beck Anxiety Inventory, CGI Clinical Global Impression, SUDS Subjective Units of Distress Scale, BDI Beck Depression Inventory, BSQ Bodily Sensations Questionnaire, EQ5D EuroQol, Tic-P Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness, SPAI Social Phobia and Anxiety Inventory, LSAS Liebowitz Social Anxiety Scale, PDSS Panic Disorder Severity Scale, MI Mobility Inventory, ACQ Agoraphobic Cognitions Questionnaire