Table 4.

Mutations in CSF cell samples detected with different pipelines

Patients	CFS cell Mutation sites/ (DNA input)
	cHOPE	OncoAim	ddCAP	ddCAP on Tissue
#1	EGFR L747_E749del	NA	NA	NA
	(8 ng)
#2	No mutation	NA	No mutation	NA
	(11 ng)		(20 ng)
#3	No mutation	NA	NA	NA
	(14 ng)
#4	EGFR E746_A750del; TP53 R158L	NA	TP53 R158L	NA
	(9 ng)		(30 ng)
#5	ALK G689R; EGFR L858R (20 ng)	NA	NA	EGFR L858R (50 ng)
#6	EGFR E746Valfs, P753Rfs (20 ng)	EGFR E746_P753 > VS (20 ng)	NA	NA
#7	NA	NA	NA	EGFR L858R
				(50 ng)
#8	NA	NA	No mutation	NA
			(7 ng)
#9	TP53 W53	NA	NA	TP53 W53
	(5 ng)			(50 ng)
#10	NA	NA	EGFR L858R	NA
			(30 ng)
#11	EGFR L858R; TP53 D228Valfs	EGFR L858R	NA	NA
	(8 ng)	(20 ng)
#12	TP53 V272 M; EGFR E746_A750del	NA	NA	TP53 V272 M;
	(10 ng)			(50 ng)
#19	NA	NA	NA	EGFR E746_A750del
				(50 ng)

NA not available