Table 2.

Summary of outcome measures for OxCaMS

Primary outcome

The effect of L-type voltage-gated calcium channel (LTCC) antagonism on cognitive instability

Secondary outcomes

The effect of LTCC antagonism on mood instability

The effect of LTCC antagonism on physical activity and sleep

The effect of LTCC antagonism on neural dynamics, at rest and during task performance

The effect of LTCC antagonism on heart rate variability

The effect of LTCC antagonism on calcium channel expression and calcium signalling

The effect of rs1006737 genotype and its interaction with LTCC antagonism on the above measures