Table 1.
SMAART Cohort Baseline Demographics and Pregnancy Outcomes (Spontaneous Group vs Infertility Group)
| Spontaneous Group (n = 208) | Infertility Group (n = 201) | P Value | |
|---|---|---|---|
| Baseline demographics | |||
| Maternal age, years | 39 ± 2.7 | 40 ± 3.0 | 0.019a |
| Paternal age, years (n = 207,193) | 40 ± 5.0 | 41 ± 8.3 | 0.472 |
| Maternal race | 0.034a | ||
| White | 181 (87) | 165 (82) | |
| Asian | 21 (10) | 24 (12) | |
| Black | 5 (2.4) | 2 (1) | |
| Biracial (white/Asian) | 1 (0.48) | 2 (1) | |
| Biracial (other) | 0 | 8 (4) | |
| Paternal race | 0.492 | ||
| Sex of fetus | 0.348 | ||
| Male | 109 (52) | 96 (48) | |
| Female | 99 (48) | 105 (52) | |
| Fetal race | 0.135 | ||
| White | 170 (82) | 154 (77) | |
| Asian | 6 (2.9) | 6 (3) | |
| Black | 5 (2.4) | 1 (0.5) | |
| Biracial (white/Asian) | 23 (11) | 28 (14) | |
| Biracial (other) | 4 (1.9) | 10 (5) | |
| Multiracial | 0 | 2 (1) | |
| Maternal BMI, kg/m2 (n = 205,193) | 23 ± 4.1 | 24 ± 4.9 | 0.133 |
| Hypertension | 5 (2.4) | 5 (2.5) | 0.956 |
| Diabetes | 3 (1.4) | 8 (4) | 0.113 |
| Thyroid disease | 26 (13) | 40 (20) | 0.042a |
| Other | 9 (4.3) | 5 (2.5) | 0.306 |
| Gestational age at CVS, days | 82 ± 6.6 | 82 ± 6.5 | 0.832 |
| Crown rump length, mm (n = 203,195) | 54 ± 12 | 53 ± 11 | 0.619 |
| Pregnancy outcomes | |||
| Gestational age at delivery, days (n = 197,184) | 273 ± 12 | 272 ± 14 | 0.499 |
| Birth weight, g (n = 183,171) | 3350 ± 548 | 3303 ± 582 | 0.436 |
| Mode of delivery (n = 200,182) | <0.001a | ||
| Vaginal, spontaneous | 126 (63) | 76 (42) | |
| Cesarean section | 74 (37) | 106 (58) | |
| Pregnancy complications (n = 202,190) | 30 (15) | 44 (23) | 0.036a |
| Hypertension | 13 (6.3) | 14 (7) | 0.771 |
| Diabetes | 18 (8.7) | 26 (13) | 0.162 |
| Coagulation disorders | 0 | 2 (1) | 0.149 |
| Placenta previa | 3 (1.4) | 5 (2.5) | 0.445 |
| Placental abruption | 1 (0.48) | 1 (0.5) | 0.981 |
| Other placental complication | 0 | 4 (2) | 0.041a |
Data given as no. (%) or mean ± SD.
Abbreviation: CVS, chorionic villus sampling.
a
P < 0.05. Number of observations, if different, is noted.