Table 2.
SMAART Cohort Baseline Demographics and Pregnancy Outcomes (Groups: Spontaneous vs NIFT vs IVF)
| Spontaneous Group (n = 208) | NIFT Group (n = 90) | IVF Group (n = 111) | P Value | P Value | |||
|---|---|---|---|---|---|---|---|
| Spontaneous vs NIFT |
Spontaneous vs IVF
|
NIFT vs IVF
|
|||||
| Baseline demographics | |||||||
| Maternal age, years | 39 ± 2.7 | 39 ± 2.9 | 40 ± 3.0 | 0.029a | 0.879 | 0.023a | 0.604 |
| Paternal age, years (n = 207;83;110) | 40 ± 5.0 | 39 ± 6.3 | 42 ± 9.4 | 0.004a | 0.371 | 0.055 | 0.003a |
| Maternal race | 0.012a | ||||||
| White | 181 (87) | 73 (81) | 92 (83) | ||||
| Asian | 21 (10) | 11 (12) | 13 (12) | ||||
| Black | 5 (2.4) | 0 | 2 (1.8) | ||||
| Biracial (white/Asian) | 1 (0.48) | 0 | 2 (1.8) | ||||
| Biracial (other) | 0 | 6 (6.7) | 2 (1.8) | ||||
| Paternal race | 0.357 | ||||||
| Sex of fetus | 0.234 | ||||||
| Male | 109 (52) | 48 (53) | 48 (43) | ||||
| Female | 99 (48) | 42 (47) | 63 (57) | ||||
| Fetal race | 0.053 | ||||||
| White | 170 (82) | 67 (74) | 87 (78) | ||||
| Asian | 6 (2.9) | 1 (1.1) | 5 (4.5) | ||||
| Black | 5 (2.4) | 0 | 1 (0.9) | ||||
| Biracial (white/Asian) | 23 (11) | 13 (14) | 15 (14) | ||||
| Biracial (other) | 4 (1.9) | 8 (8.9) | 2 (1.8) | ||||
| Multiracial | 0 | 1 (1.1) | 1 (0.9) | ||||
| Maternal BMI, kg/m2 (n = 205;90;103) | 23 ± 4.1 | 24 ± 5.8 | 23 ± 3.9 | 0.055 | |||
| Hypertension | 5 (2.4) | 4 (4.4) | 1 (0.9) | 0.270 | |||
| Diabetes | 3 (1.4) | 3 (3.3) | 5 (4.5) | 0.250 | |||
| Thyroid disease | 26 (13) | 15 (17) | 25 (23) | 0.067 | |||
| Other | 9 (4.3) | 2 (2.2) | 3 (2.7) | 0.582 | |||
| Gestational age at CVS, days | 82 ± 6.6 | 81 ± 6.3 | 82 ± 6.6 | 0.683 | |||
| Crown rump length, mm (n = 203;86;109) | 54 ± 12 | 53 ± 11 | 53 ± 12 | 0.825 | |||
| Pregnancy outcomes | |||||||
| Gestational age at delivery, days (n = 197;82;102) | 273 ± 12 | 273 ± 11 | 271 ± 16 | 0.507 | |||
| Birth weight, g (n = 183;80;91) | 3350 ± 548 | 3328 ± 583 | 3281 ± 587 | 0.634 | |||
| Mode of delivery (n = 200;82;100) | <0.001a | ||||||
| Vaginal, spontaneous | 126 (63) | 42 (51) | 34 (34) | ||||
| Cesarean section | 74 (37) | 40 (49) | 66 (66) | ||||
| Pregnancy complications (n = 202;86;104) | 30 (15) | 18 (21) | 26 (25) | 0.085 | |||
| Hypertension | 13 (6.3) | 7 (7.8) | 7 (6.3) | 0.878 | |||
| Diabetes | 18 (8.7) | 12 (13) | 14 (13) | 0.372 | |||
| Coagulation disorders | 0 | 1,1.1) | 1 (0.9) | 0.346 | |||
| Placenta previa | 3 (1.4) | 0 | 5 (4.5) | 0.054 | |||
| Placental abruption | 1 (0.48) | 0 | 1 (0.9) | 0.660 | |||
| Other placental complication | 0 | 1 (1.1) | 3 (2.7) | 0.065 | |||
Data given as no. (%) or mean ± SD.
Abbreviation: CVS, chorionic villus sampling.
a
P < 0.05. Number of observations, if different, is noted.