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. 2019 Feb 6;10:177. doi: 10.3389/fmicb.2019.00177

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Copyright © 2019 Zhou, Xiong, Yin, Zou, Wang, Shao and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lysozyme mediated changes in serum indices and correlations with gut microbiota. (A) Serum aspartate transaminase (AST), (B) serum alanine transaminase (ALT), (C) AST/ALT ratio, (D–F). Serum immunoglobulins, IgM (D), IgA (E), and IgG (F). (G) Heatmap of the Spearman r correlations between the gut microbiota significantly modified serum biochemical makers after 21-day lysozyme supplementation. ^∗P < 0.05, ^∗∗P < 0.01 (following the Spearman correlation analysis). BUN, blood urea nitrogen; CREA, creatinine; TG, triglycerides; GLU, glucose; HDL-C, LDL-C, high- and low-density lipoprotein cholesterol; CHO, cholesterol; AST, aspartate transaminase; ALT, alanine transaminase; TP, total protein; ALB, albumin; GLO, globulin; A/G, albumin/globulin ratio.