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. 2018 Nov 13;33(1):17–25. doi: 10.1007/s00540-018-2577-6

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Expression of Grp78 after application of bupivacaine and levobupivacaine. Representative western blots and band density analysis of Grp78 in a Caco2 cells and d A375 cells. Grey scale of intensity values expressed as ratio relative to GAPDH. Representative immunofluorescence images of Grp78 in b Caco2 cells and e A375 cells (×20 magnification; nuclei counterstained with DAPI; scale bar = 50 µm). Immunofluorescence intensity of Grp78 in (C) Caco-2 cells and (F) A375 across different treatment groups (n = 4, data shown as mean ± SD; *p < 0.05; NC naïve control, VC vehicle control, Bupi 24 h treatment of 1 mM Bupivacaine, L-Bupi 24 h treatment of 1 mM Levobupivacaine)