Table 3.
Multivariate (Cox proportional hazard regression) analysis
| Variables | P value | Exp (B) | 95% Confidence interval for Exp (B) | |
|---|---|---|---|---|
| Lower | Upper | |||
| Multivariate (overall survival) (239 patients) | ||||
| Age (median 62) | 0.225 | 1.253 | 0.870 | 1.805 |
| Grade | 0.177 | 1.445 | 0.847 | 2.465 |
| FIGO stage | 0.001 | 1.513 | 1.192 | 1.919 |
| Histological subtypes | 0.833 | 0.983 | 0.836 | 1.155 |
| Platinum sensitivity | < 0.001 | 3.142 | 2.024 | 4.879 |
| Tumour residue | 0.029 | 1.298 | 1.028 | 1.639 |
| Calpastatin expression | 0.061 | 0.711 | 0.498 | 1.015 |
| Multivariate (overall survival) (238 patients) | ||||
| Age (median 62) | 0.059 | 1.404 | 0.987 | 1.998 |
| Grade | 0.138 | 1.527 | 0.873 | 2.673 |
| FIGO stage | < 0.001 | 1.540 | 1.209 | 1.962 |
| Histological subtypes | 0.959 | 1.004 | 0.855 | 1.180 |
| Platinum sensitivity | < 0.001 | 3.272 | 2.107 | 5.082 |
| Tumour residue | 0.031 | 1.283 | 1.023 | 1.610 |
| Calpain-2 expression | 0.070 | 1.524 | 0.967 | 2.404 |
| Multivariate (overall survival) (239 patients) | ||||
| Age (median 62) | 0.164 | 1.296 | 0.900 | 1.867 |
| Grade | 0.201 | 1.427 | 0.828 | 2.462 |
| FIGO stage | 0.001 | 1.497 | 1.178 | 1.904 |
| Histological subtypes | 0.801 | 0.979 | 0.832 | 1.152 |
| Platinum sensitivity | < 0.001 | 3.088 | 1.987 | 4.798 |
| Tumour residue | 0.023 | 1.303 | 1.037 | 1.639 |
| Calpain-4 expression | 0.232 | 0.793 | 0.542 | 1.160 |
Significant P values are indicated by bold type
Exp(B) is used to denote hazard ratio