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. 2018 Nov 28;46(2):133–145. doi: 10.1007/s10295-018-2107-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — Investigation of molecular changes based on electrophoretic karyotypes. Karyotypes of strains isolated after every 80 generations from co-culture evolved lines (Line A–Line C), and control lines (D–F) are shown. Extrapolation from the migration of marker strains of S. pombe (SJA148) and S. cerevisiae (S288C) was carried out to estimate the size of the novel bands at approximately 1.8 Mb (red arrow)