Fig. 3.

(a) Mean serum insulin aspart concentration–time profiles for faster aspart and insulin aspart. Patients with T1D received a single subcutaneous dose of 0.2 U/kg faster aspart or insulin aspart, and blood samples for serum insulin aspart were taken for 12 h. (b) Rate of absorption relative to the amount of insulin aspart in the subcutaneous depot (deconvolution approach). Lines between data points were linearly interpolated. Data shown as mean ± SEM. (c) Absorption rate constant profiles (population modelling approach). Data shown as geometric mean and 95% CI. Part 3A adapted from Heise et al. Diabetes Obes Metab 2015:17;682–688, with permission of John Wiley & Sons, © 2015. CI, confidence interval; faster aspart, fast-acting insulin aspart; SEM, standard error of the mean; T1D, type 1 diabetes.