Table II.

Composition of Insulin Aspart Samples

Sample	Insulin aspart (mM)	Zinc acetate (mM)	Phenol (mM)	m-cresol (mM)	Arginine hydrochloride (mM)	Niacinamide (mM)	Phosphate (mM)	pH
1	0.6	0.3	16	16	20	170	3	7.1
2	0.6	0.3	16	16	20	-	3	7.1
3	0.6	0.3	-	-	20	170	3	7.1
4	0.6	0.3	-	-	20	-	3	7.1

Samples were diluted 1:1 in HBSS buffer prior to the SAXS measurements. Samples used for background subtraction were identical, but did not contain insulin aspart. Samples containing 1-methyl-niacinamide, a non-functional niacinamide analogue, were used as a negative control. HBSS, Hank's Balanced Salt Solution; SAXS, small angle X-ray scattering