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Absolute lymphocyte count time-course profiles (treatment scenario 2). The blue dashed line denotes the upper limit for Grade 1 lymphopenia (1.0 × 109 cells/L). The red dashed lines denote upper limits for Grades 2, 3 and 4 lymphopenia (0.8, 0.5 and 0.2 × 109 cells/L, respectively). ALC absolute lymphocyte count
