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Treatment algorithms to postpone treatment at the start of year 2 in patients with Grade 2–4 lymphopenia
| Treatment scenario | Postponement block duration (months) |
Maximum postponement durationa (months) |
|---|---|---|
| 1 | 1 | 3 |
| 2 | 2 | 6 |
| 3 | 3 | 9 |
Lymphopenia graded by the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0 [13]; Grade 2: 0.5 to < 0.8 × 109 cells/L; Grade 3: 0.2 to < 0.5 × 109 cells/L; Grade 4: < 0.2 × 109 cells/L
aMaximum delay was three blocks in each scenario
