Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 19;224(1):373–386. doi: 10.1007/s00429-018-1775-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 2 — Bmal1 deficiency affects the number of newly developed neurons reaching the olfactory bulb within 4 days. Representative photomicrographs and quantification of BrdU-immunopositive cells (arrows) in the olfactory bulb of Bmal1^+/+ mice (+/+) and Bmal1^−/− mice (-/-). BrdU immunoreaction (brown precipitate) and cresyl violet staining (blue) in (a) granule cell layer (b) glomerular layer. Immunofluorescence for BrdU and DCX, as a marker of newly developed neurons, and quantification of DCX⁺/BrdU⁺ cell as percentage of total BrdU⁺ cells in (c) granule cell layer, (d) glomerular layer, arrowheads indicate DCX⁺ cells, glomeruli are indicated by circles. *P < 0.05, n = 4 mice per genotype. Scale bars = 50 µm