Table 1.
Study | Area | Race | Type of cancer | No. of cases | No. of controls | Genotypes in case group n (%) | Genotypes in controls n (%) | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Arg326Gln (R326Q) (rs1503185) | Arg326Gln (R326Q) (rs1503185) | ||||||||||
RR | RQ | RR | RQ | ||||||||
Iuliano et al. 2004 | Italy | Caucasian | TA TC |
22 66 |
54 54 |
11 45 |
10 17 |
1 4 |
32 32 |
20 20 |
2 2 |
Mita et al. 2010 | Japan | Asian | LAD LSQ HNSCC CRC ESCC |
108 59 92 113 193 |
819 819 819 819 819 |
66 36 58 51 106 |
34 17 27 45 77 |
8 6 7 17 10 |
510 510 510 510 510 |
272 272 272 272 272 |
37 37 37 37 37 |
Wei et al. 2013 | China | Japan | BC | 199 | 198 | 104 | 75 | 20 | 87 | 92 | 19 |
TA thyroid adenoma, TC thyroid carcinoma, CRC colorectal cancer, LAD lung adenocarcinoma, LSQ lung squamous cell carcinoma, HNSCC head and neck squamous cell carcinoma, ESCC oesophageal cancer, BC breast cancer