TABLE 3.

Spearman correlation coefficients and regression P values for log-rank–transformed formate data on blood metabolites in the study population

Metabolite	Formate, Spearman’s r	P 1
Methionine	0.088	1.20 × 10−4
Serine	0.130	1.5 × 10−7
Glycine	−0.082	0.016
Tryptophan	0.122	5.82 × 10−7
Serum folate	0.124	1.67 × 10−5
Homocysteine	−0.081	6.03 × 10−5
Serum total vitamin B-12	−0.081	7.61 × 10−4
Choline	0.091	1.07 × 10−4
Cysteine	−0.037	0.150
Cystathionine	0.035	0.105
Red blood cell folate	0.000	0.921
Holotranscobalamin	−0.031	0.674
Methylmalonic acid	0.006	0.268

¹ P values are based on the following models: y = α₀ + α₁x + ε, where y = inverse normal rank transformation of formate and x is one of the metabolites. The P value is for the null H₀: α₁ = 0.