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. Author manuscript; available in PMC: 2019 Feb 13.
Published in final edited form as: Dig Dis Sci. 2018 Jul 24;63(11):2910–2922. doi: 10.1007/s10620-018-5216-z

Fig. 2.

Fig. 2

Macroscopic observations of colon length and reduction of colon length in GPR35+/+ and GPR35−/− mice administered DSS. a Representative macroscopic observations of colon length. b Bar graph showing colon length of GPR35+/+ alone, GPR35−/− alone, GPR35+/+ + DSS, and GPR35−/− + DSS groups. After administration with 5 days of DSS and 1 day of water, the colons of GPR35−/− mice showed significant shortening compared to those of GPR35+/+ mice. **p < 0.01 versus GPR35+/+ alone; ##p < 0.01 versus GPR35+/+ + DSS. c Percentage of colon length reduction in GPR35+/+ and GPR35−/− mice after DSS administration. A significant reduction of colon length was observed in GPR35−/− compared to GPR35+/+ mice upon DSS administration. N = 10 (GPR35+/+ alone), n = 6 (GPR35−/− alone), n = 10 (GPR35+/+ + DSS), n = 8 (GPR35−/− + DSS). *p < 0.05 versus GPR35+/+ alone; #p < 0.05 versus GPR35+/+ + DSS