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. Author manuscript; available in PMC: 2019 Feb 13.
Published in final edited form as: Dig Dis Sci. 2018 Jul 24;63(11):2910–2922. doi: 10.1007/s10620-018-5216-z

Fig. 7.

Fig. 7

GPR35 deficiency affects the expression of cell junction molecules. Colorectal epithelial cells (Caco2) were transfected with siRNA targeting GPR35 (GPR35 KD) or non-targeting siRNA which was used as control (control). Then the cells were treated with or without 1% DSS for 4 h (n = 3 biological repeats). The expression of ZO-1, E-cadherin, and Claudin1 was decreased in GPR35 deficiency cells. DSS treatment resulted in decrease in ZO-1, E-cadherin, and Claudin1, but the decreases in ZO-1 and Claudin1 were more severe in GPR35 knockdown cells