Comparison 2. Ranolazine (monotherapy) any dose versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 AMI incidence	3	2983	Risk Ratio (M‐H, Fixed, 95% CI)	0.88 [0.69, 1.12]
2 Angina episodes frequency	2	402	Mean Difference (IV, Fixed, 95% CI)	0.08 [‐0.85, 1.01]
3 Adverse events incidence	3	947	Risk Ratio (M‐H, Fixed, 95% CI)	1.50 [1.12, 2.00]
3.1 Macrovascular angina	2	691	Risk Ratio (M‐H, Fixed, 95% CI)	1.53 [1.13, 2.07]
3.2 Microvascular angina	1	256	Risk Ratio (M‐H, Fixed, 95% CI)	1.17 [0.40, 3.38]