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Hydroxyl radical footprints obtained with recombinant histone nucleosomes assembled from the 147-mer 601cP DNA sequences containing S-cdA lesions at the Out and In rotational settings. (A) Autoradiograph of a typical hydroxyl radical footprint experiment. (B) Scan of the results shown (A) in the region containing the lesions (red vertical bar), and (C) Scan of the entire sequence.
