Table 1.
Baseline Characteristics
| Docetaxel (N=41) | AXL1717 (N=58) | Total (N=99) | ||
|---|---|---|---|---|
| Age | ||||
| Mean (SD) | 58.6 (7.6) | 57.5 (7.0) | 57.9 (7.2) | |
| Median | 58 | 57 | 57 | |
| Range | 44 to 73 | 42 to 81 | 42 to 81 | |
| n | 41 | 58 | 99 | |
| Gender | n (%) | |||
| Female | 10 (24) | 18 (31) | 28 (28) | |
| Male | 31 (76) | 40 (69) | 71 (72) | |
| Histology | n (%) | |||
| Adenocarcinoma | 20 (49) | 29 (50) | 49 (49) | |
| Squamous cell carcinoma | 21 (51) | 29 (50) | 50 (51) | |
| WHO Performance status | n (%) | |||
| 0 | 12 (29) | 12 (21) | 24 (24) | |
| 1 | 28 (68) | 43 (74) | 71 (72) | |
| 2 | 1 (2) | 3 (5) | 4 (4) | |
| Hgb | ||||
| Mean (SD) | 126 (17) | 125 (16) | 125 (16) | |
| Median | 125 | 122 | 124 | |
| Range | 92 to 167 | 93 to 164 | 92 to 167 | |
| n | 40 | 57 | 97 | |
| Hgb | n (%) | |||
| <110 g/L | 6 (15) | 11 (19) | 17 (18) | |
| ≥110 g/L | 34 (85) | 46 (81) | 80 (82) | |
| WBC | ||||
| Mean (SD) | 8.3 (3.7) | 8.1 (2.8) | 8.2 (3.1) | |
| Median | 7.3 | 7.3 | 7.3 | |
| Range | 3.8 to 19.9 | 3.8 to 15.5 | 3.8 to 19.9 | |
| n | 41 | 58 | 99 | |
| WBC | n (%) | |||
| ≤9 x 109/L | 29 (71) | 37 (64) | 66 (67) | |
| >9 x 109/L | 12 (29) | 21 (36) | 33 (33) | |
| Plt | ||||
| Mean (SD) | 313 (102) | 307 (98) | 309 (99) | |
| Median | 301 | 276 | 284 | |
| Range | 155 to 668 | 196 to 588 | 155 to 668 | |
| n | 40 | 57 | 97 | |
| Plt | n (%) | |||
| ≤350 x 109/L | 27 (68) | 44 (77) | 71 (73) | |
| >350 x 109/L | 13 (33) | 13 (23) | 26 (27) | |
Hgb, Hemoglobin; WBC, White blood cells; Plt, Platelets; SD, Standard deviation