Table 3.

Non-BrCa Cell Content Regulation.

Exosomal Contents	Origin	Isolation/Detection Method	Application	Ref.
miR-233	Human macrophages	RT-qPCR	Promotes breast cancer cell invasion	Yang et al 109
The quantity of exosomes	Human mammary epithelial cell line(HMEC B42)	Nanosight LM10 analysis, western blot and PKH labeled	Regulate BrCa cell derived exosomes released	Riches et al 110
ADAM10	Fibroblast	Antibodies and qRT-PCR primers or primer/probe sets	Breast cancer cell mobilization and proliferation	Shimoda M et al,111,112
miR-21, -378e, and -143	Cancer-associated fibroblasts	qRT-PCR	Breast cancer epithelial-mesenchymal transition	Donnarumma et al 89
miR-16	Mesenchymal stem cells	qRT-PCR	Inhibition of angiogenesis	Lee et al 113

Abbreviation: RT-qPCR, real-time quantitative polymerase chain reaction.