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. 2019 Jan 22;18:1533033818824314. doi: 10.1177/1533033818824314

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Cell cycle, apoptosis, and cell proliferation changes after miR-132 upregulation in pancreatic ductal adenocarcinoma cells. SW1990 and Panc-1 cells were transfected with control (NC) and miR-132 mimics. Lipofectamine 2000 alone was used as a blank control group. In both cell lines, increased miR-132 expression results in cells resting in the G2 phase (A, Panc-1; B, SW1990). Upregulated miR-132 expression also increases apoptosis (C, Panc-1; D, SW1990) and reduces cell proliferation (E, Panc-1; F, SW1990) in both cell lines. **P < .01; *P < .05; miR-132 group was compared with the NC group or control group separately. miR-132 indicates microRNA-132.