Table 1.
Variable | Number of Cases | MiR-132 Expression | P Value | |
---|---|---|---|---|
Low, n = 24 | High, n = 26 | |||
Age, years | .273 | |||
<59 | 19 | 11 (57.89%) | 8 (42.11%) | |
≥59 | 31 | 13 (41.94%) | 18 (58.06%) | |
Gender | .164 | |||
Male | 32 | 13 (40.63%) | 19 (59.83%) | |
Female | 18 | 11 (61.11%) | 7 (38.89%) | |
Tumor location | .369 | |||
Head | 33 | 14 (42.42%) | 19 (57.58%) | |
Others | 17 | 10 (58.82%) | 7 (41.18%) | |
CA199, U/L | .080 | |||
<37 | 14 | 4 (28.57%) | 10 (41.18%) | |
≥37 | 36 | 20 (55.56%) | 16 (44.44%) | |
CEA, ng/mL | .133 | |||
<5 | 30 | 17 (56.67%) | 13 (43.33%) | |
≥5 | 20 | 7 (35.00%) | 13 (65.00%) | |
TNMa | .469 | |||
I+II | 47 | 22 (46.81%) | 25 (53.19%) | |
III+IV | 3 | 2 (66.67%) | 1 (33.33%) | |
T stage | .496 | |||
T1+T2 | 26 | 13 (50.00%) | 13 (50.00%) | |
T3+T4 | 24 | 11 (45.83%) | 13 (54.17%) | |
N stage | .059 | |||
N0 | 33 | 19 (57.58%) | 14 (42.42%) | |
N1 | 17 | 5 (29.41%) | 12 (70.59%) | |
Differentiation | .650 | |||
Poor | 14 | 6 (42.86%) | 8 (57.14%) | |
Moderate | 36 | 18 (50.00%) | 18 (50.00%) | |
Tumor size, cmb | .775 | |||
<3.35 | 27 | 14 (51.85%) | 13 (48.15%) | |
≥3.35 | 23 | 10 (43.48%) | 13 (56.52%) | |
Vascular invasion | .273 | |||
No | 31 | 13 (41.94%) | 18 (58.06%) | |
Yes | 19 | 11 (57.89%) | 8 (42.11%) | |
Surgical marginsc | 1.000 | |||
Free | 41 | 20 (48.78%) | 21 (51.22%) | |
Not free | 9 | 4 (44.44%) | 5 (55.56%) |
Abbreviations: CEA, carcinoembryonic antigen; TNM, tumor node metastasis.
aThe seventh edition of the TNM Classification of Malignant Tumors.
b3.35 cm is a mean of tumor diameters.
c Surgical margin free is defined when there was no tumor cell inside 0.5 cm of incisal edge.