Table 1. Extinction and Reconsolidation Regulated Signaling.

Phosphopeptides found to be regulated by both extinction and reconsolidation relative to controls. The Table gives the protein name with the gene name in parentheses and the phosphopeptide from that protein identified by mass spectrometry including the site of modification denoted by a “p” prior to the modified amino acid. The additional columns show the p-value from the ANOVA and the fold change and p-value from the pair-wise comparison between the extinction (Ext) group relative to control and the reconsolidation (Recon) group relative to control. Fold changes greater than 1 represent increases in phosphopeptide abundance, while decreases are less than 1. Astericks (*) indicate where the extinction and reconsolidation groups were also significantly different from each other.

Protein (gene name)	Peptide + Modification(s)	ANOVA	Fold Change Ext vs Control	p-value	Fold Change Recon vs Control	p-value
Microtubule-associated protein 2 (Map2)	VAIIRpTPPK	0.00003	1.48*	0.041	1.15*	0.032
Microtubule-associated protein 1B (Map1b)	TTKpTPEDGGYSCEITEK	0.00005	0.68	0.068	0.41	0.079
Leucine-rich repeat-containing protein 7 (Lrrc7)	LETpTPTTpSPLPERK	0.0002	2.08	0.006	1.76	0.055
Alpha-adducin (Add1)	SPPDQSAVPNpTPPSpTPVK	0.0005	1.63	0.014	1.66	0.026
Connector enhancer of kinase suppressor of ras 2 (Cnksr2)	GSEpSPNSFLDQEYRK	0.001	4.12	0.031	2.6	0.031
Receptor-type tyrosine-protein phosphatase-like N (Ptprn)	AEDpSSEGHEEEVLGGHGEK	0.002	0.4	0.012	0.35	0.055
Beta-arrestin-1 (Arrb1)	DDKDEEDDGTGpSPHLNNR	0.012	1.56	0.067	1.55	0.051
Rho GTPase-activating protein 35 (Arhgap35)	TSFSVGpSDDELGPIR	0.013	0.61	0.069	0.69	0.005
Cell cycle exit and neuronal differentiation protein (Cend1)	ADPVLLNNHSNLKPAPTVPAAPSpSPDTTSEPK	0.015	0.35	0.015	0.4	0.027
SRC kinase signaling inhibitor 1 (Srcin1)	RGpSDELTVPR	0.015	1.52*	0.002	1.25*	0.02