Table 3. Proteins Regulated by Extinction in both the NAc and BLA.

Proteins found to be regulated by cue extinction in both the NAc and BLA. The Table gives the protein name with the gene name in parentheses and the phosphopeptide from that protein identified by mass spectrometry in the NAc and the BLA (from left to right), including the site of modification denoted by a “p” prior to the modified amino acid. The additional columns show the fold change of that phosphopeptide in the the extinction group relative to controls (Con) in the NAc and BLA (from left to right). Fold changes greater than 1 represent increases in phosphopeptide abundance, while decreases are less than 1. For two proteins (SRC kinase signaling inhibitor 1 and stathmin 1), two different phosphopeptides were identified in the BLA, but only one in the NAc.

Protein (gene name)	Phosphopeptide NAc	Phosphopeptide BLA	NAc Fold Change from Con	BLA Fold Change from Con
Gamma-aminobutyric acid type B receptor subunit 2 (Gabbr2)	DPIEDINpSPEHIQR	DPIEDINpSPEHIQR	1.35	1.23
Syntaxin-1A (Stx1a)	TAKDpSDDDDDVTVTVDRDR	TAKDpSDDDDDVTVTVDRDR	1.61	1.19
Caskin-1 (Caskin1)	KVPLPGPGpSPEVK	KVPLPGPGpSPEVK	1.24	0.77
Receptor-type tyrosine-protein phosphatase-like N (Ptprn)	AEDpSSEGHEEEVLGGHGEK	LPEEGGSpSRAEDSpSEGHEEEVLGGHGEK	0.4	1.27
Sodium channel protein type 2 subunit alpha (Scn2a)	GKEDEGpTPIKEDIITDK	RFSpSPHQpSLLSIR	1.16	1.12
SRC kinase signaling inhibitor 1 (Srcin1)	RGpSDELTVPR	DSGSSSVFAEpSPGGK	1.52	1.14
	RGpSDELTVPR	RFpSNVGLVHTSER	1.52	0.77
Stathmin (Stmn1)	DLpSLEEIQK	ESVPEFPLpSPPK	1.34	0.92
	DLpSLEEIQK	RASpGQAFELILpSPR	1.34	1.26
Protein bassoon (Bsn)	pSLSDPKPLpSPTAEESAK	SPQVLYpSPVpSPLSPHR	1.64	1.25
Misshapen-like kinase 1 (Mink1)	LDSpSPVLSPGNK	SDSVLPASHGHLPQAGpSLER	1.76	1.13
SH3 and multiple ankyrin repeat domains protein 3 (Shank3)	SApSDINLK	SRpSPpSPpSPLPSPSPGSGPSAGPR	2.49	1.21