Table 1:

Binding affinities of (S)-1 and analogs against known kinase targets.

Compound Number	TRKC Kd	CDKL2 Kd
(S)-1	200 nM	260 nM
(R)-1	400 nM	1,200 nM
5	NB	NB
6	2,600 nM	19,000 nM

NB= No significant binding