Table 4:
Model averaged parameters and 95% CI’s for all model terms and CFL, BNT, Digit Span Forwards, Digit Span Backwards, and 4 Test IICV
| Model term | Boston Naming | Digit Span Forwards | Digit Span Backwards | Sqrt 4 test IICV |
|---|---|---|---|---|
| SES | 0.012 (−0.052, 0.075) | −0.001 (−0.116, 0.111) | 0.031 (−0.08, 0.145) | −0.003 (−0.013, 0.006) |
| SES^ | −0.053 (−0.095, −0.001) | −0.05 (−0.121, 0.024) | −0.032 (−0.105, 0.048) | 0.001 (−0.006, 0.008) |
| URG | −0.695 (−0.888, −0.487) | −0.346 (−0.794, 0.1) | −0.26 (−0.719, 0.194) | −0.021 (−0.056, 0.016) |
| Male | 0.225 (0.122, 0.353) | 0.344 (0.102, 0.628) | 0.22 (−0.041, 0.425) | 0.022 (1.97E-04, 0.043) |
| Age | 0.014 (0.009, 0.02) | −0.014 (−0.025, −0.006) | 0.004 (−0.004, 0.018) | 0.001 (2.79E-04, 0.002) |
| ESL | −0.672 (−0.983, −0.351) | −0.236 (−1.068, 0.604) | 0.012 (−0.796, 0.849) | 0.007 (−0.057, 0.073) |
| Male x Age | −1.29E–05 (−0.011, 0.001) | −1.59E–04 (−0.016, 0.016) | −0.001 (−0.03, 0.004) | 2.10E–04 (−0.002, 0.002) |
| one APOE ε4 | −8.14E–08 (−0.209, 0.005) | 0.001 (−0.042, 0.21) | −0.007 (−0.192, 0.046) | −3.21E–14 (−4.89E–08, 3.58E–11) |
| two APOE ε4 | 0.024 (−0.004, 0.437) | −0.002 (−0.268, 0.201) | 0.011 (−0.125, 0.399) | 9.65E–15 (−5.56E–09, 2.23E–08) |
| Male x one APOE ε4 | −1.06E–07 (−0.008, 8.98E–08) | −0.005 (−0.597, 3.04E–04) | −4.96E–05 (−0.058, 0.003) | 2.64E–18 (−7.61E–14, 8.71E–12) |
| Male x two APOE ε4 | −1.16E–07 (−0.007, 2.82E–04) | −0.005 (−1.054, 0.292) | −3.87E–04 (−0.243, 9.44E–05) | −6.43E–18 (−1.29E–11, 1.19E–12) |
| Age x one APOE ε4 | 1.39E–10 (−1.23E–07, 5.44E–06) | 4.99E–07 (−8.04E–05, 1.57E–04) | −2.01E–05 (−0.019, 1.01E–07) | 2.79E–15 (−4.45E–12, 6.67E–09) |
| Age x two APOE ε4 | −2.89E–11 (−4.74E–06, 2.76E–06) | −4.76E–07 (−2.38E–04, 2.25E–04) | 1.72E–05 (−0.001, 0.016) | 1.07E–14 (−1.20E–13, 2.41E–08) |
| Age^2 | −0.001 (−0.002, −0.001) | −0.001 (−0.002, −2.19E–05) | −0.001 (−0.003, −5.34E–05) | 1.69E–04 (1.39E–05, 2.73E–04) |
| Male x Age^2 | 1.68E–06 (−5.65E–07, 0.001) | 3.14E–04 (−1.75E–05, 0.003) | 1.74E–04 (−4.14E–06, 0.003) | −2.03E–04 (−3.78E–04, −1.23E–05) |
| Age^2 x one APOE ε4 | −4.22E–53 (−1.58E–40, 3.89E–45) | 3.68E–48 (−2.02E–39, 2.70E–37) | −4.83E–47 (−1.31E–36, 9.17E–40) | 1.36E–27 (−5.71E–27, 3.12E–18) |
| Age^2 x two APOE ε4 | −2.89E–52 (−2.67E–40, 6.78E–44) | −3.50E–48 (−8.37E–38, 5.21E–38) | −8.24E–47 (−1.58E–36, 1.02E–38) | 1.30E–27 (−9.95E–21, 1.21E–18) |
| Male x Age x one APOE ε4 | 9.19E–52 (−6.53E–53, 8.76E–39) | 8.40E–48 (−5.94E–42, 2.10E–35) | −6.06E–48 (−3.05E–36, 2.26E–39) | −3.26E–27 (−2.33E–17, 9.20E–25) |
| Male x Age x two APOE ε4 | −2.59E–51 (−7.83E–39, 8.47E–42) | −2.61E–47 (−1.42E–35, 3.11E–38) | 4.18E–48 (−2.58E–38, 7.81E–36) | −1.06E–26 (−8.36E–17, 2.84E–23) |
| WRAT reading | 0.046 (0.038, 0.051) | 0.073 (0.053, 0.083) | 0.079 (0.059, 0.087) | −0.003 (−0.004, −0.002) |
| Male x WRAT reading | 2.60E–05 (−1.06E–05, 0.018) | 0.014 (3.42E–04, 0.051) | 0.003 (2.05E–05, 0.043) | 0.007 (0.005, 0.009) |
| Age x WRAT reading | 9.30E–05 (−2.52E–05, 0.001) | 1.62E–04 (−3.61E–04, 0.002) | −1.03E–04 (−0.001, 0.001) | 3.28E–04 (2.05E–04, 4.61E–04) |
| Age^2 x WRAT reading | −1.48E–06 (−2.56E–05, 2.95E–05) | 2.75E–05 (1.70E–07, 1.60E–04) | 6.62E–06 (−4.67E–05, 1.05E–04) | 4.44E–06 (−5.00E–06, 1.50E–05) |
| Male x Age x WRAT reading | 2.61E–07 (−4.02E–04, 0.001) | −3.42E–04 (−0.003, 1.45E–04) | −1.35E–04 (−0.003, 2.30E–04) | 1.43E–04 (−6.86E–05, 3.42E–04) |
| Male x Age^2 x WRAT reading | −5.76E–08 (−6.12E–05, 1.94E–05) | −1.95E–05 (−2.06E–04, 4.47E–05) | −4.03E–06 (−1.41E–04, 7.72E–05) | −6.68E–06 (−2.05E–05, 7.43E–06) |
| Male x Age^2 x one APOE ε4 | 8.12E–53 (−1.04E–53, 7.22E–40) | 1.19E–49 (−8.64E–40, 9.43E–38) | −2.76E–49 (−9.82E–38, 1.01E–39) | −2.78E–28 (−2.07E–18, 1.01E–25) |
| Male x Age^2 x two APOE ε4 | 1.10E–52 (−4.00E–44, 5.31E–40) | −4.20E–49 (−2.62E–37, 7.14E–39) | −1.92E–48 (−1.38E–36, 1.55E–40) | −1.64E–29 (−1.13E–20, 1.08E–18) |
Note: “E” represents “x10^”; e.g. 1.23E–04 = 1.23×10^−4
95% CI’s that do not overlap 0 (are significant) are identified by bold-face font; gray shading denotes CIs that overlap 0.