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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Hypertension. 2019 Mar;73(3):630–639. doi: 10.1161/HYPERTENSIONAHA.118.12378

Figure 1.

Figure 1

(A) Mean arterial pressure (MAP; 24 hrs average) was measured by telemetry in rats fed a 0.4% NaCl diet for 7 days the final 4 days of which rats were treated with PP242 or vehicle prior to switching to 4.0% NaCl diet for 21 days. Open circles represent PP242 (n=7) and black circles represent vehicle (n=7) treated SS rats. * Significant difference between vehicle and PP242 treated SS rats (P<0.05) as determined using a two-way RM ANOVA; Holm-Sidak post hoc. (B) Hypertrophic index was determined by measuring the ratio of right kidney weight (gm) and total body weight (gm) of these rats.