Fig. 1.

Maternal metabolites associated with newborn outcomes across ancestries. Forest plot depicting maternal metabolites after fasting and at 1 h in the OGTT that are significantly associated with newborn birthweight (a), cord blood C-peptide (b) and/or newborn SSF (c). The x-axis represents the standardised β of each individual metabolite. Analyses were adjusted for field centre, mean arterial pressure, maternal age, neonatal sex, sample storage time, maternal height and gestational age at delivery (model 1). Model 2 included model 1 covariates and maternal BMI; model 3 included model 1 covariates and fasting or 1 h maternal glucose for the corresponding fasting or 1 h metabolite levels. Squares, model 1; circles, model 2; diamonds, model 3. AC, acylcarnitine