Table II.
Familiarity with precision medicine terms
| Question: How familiar are you with the following words or phrases?a |
Overall Sample N=252 % |
Ethnic / Racial Groups | Health Literacyb | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| White N=63 % |
African American/ Black N=107 % |
Hispanic/ Latino N=65 % |
African American/Black vs. White |
Hispanic/Latino vs. White |
Low ≤9 N= 35 % |
Adequate ≥10 N= 217 % |
HLit as a continuous variable |
|||||
| B(SE) | Β | B(SE) | β | B(SE) | β | |||||||
| General | ||||||||||||
| Precision medicine | 23.8 | 15.9 | 23.6 | 28.1 | .39(.23) | .14 | .23(.37) | .07 | 20.0 | 24.7 | .12(.04) | .22 |
| Personalized medicine | 37.3 | 39.7 | 32.7 | 42.9 | .02(.23) | .01 | .03(.38) | .01 | 34.3 | 38.7 | .09(.04) | .17 |
| Genetics | ||||||||||||
| Gene | 63.9 | 73.0 | 61.7 | 52.3 | −.04(.20) | −.02 | −.15(.33) | −.05 | 34.3 | 68.7 | .16(.04) | .30* |
| Genomics | 32.9 | 48.4 | 26.7 | 23.8 | −.41(.22) | −14 | −22(.36) | −07 | 18.2 | 36.0 | .10(.04) | .18 |
| DNA | 71.0 | 82.3 | 71.7 | 60.3 | .02(.19) | .01 | −40(.31) | −15 | 48.6 | 76.1 | .13(.04) | .28* |
| Chromosome | 58.7 | 71.4 | 52.3 | 54.7 | −13(.20) | −05 | −17(.33) | −06 | 34.3 | 63.0 | .13(.04) | .25* |
| Hereditary | 67.5 | 79.4 | 61.9 | 68.3 | −12(.20) | −05 | −15(.34) | −05 | 44.1 | 72.8 | .11(.04) | .21 |
| Biobank | 17.9 | 12.7 | 18.1 | 20.3 | .25(.21) | .09 | −24(.35) | −08 | 5.9 | 20.0 | .11(.04) | .21 |
| Genetic testing | 56.3 | 66.7 | 50.5 | 54.0 | −15(.21) | −06 | −.12(.34) | −04 | 35.3 | 60.2 | .13(.04) | .24* |
| Biological indicators | 37.3 | 42.9 | 35.5 | 28.1 | −05(.23) | −02 | −37(.38) | −11 | 14.3 | 41.4 | .15(.04) | .26* |
| Biomarkers | 24.9 | 33.3 | 18.9 | 18.8 | −26(.21) | −09 | −30(.35) | −10 | 11.4 | 27.1 | .12(.04) | .22* |
| Pharmacogenomics | 19.0 | 17.7 | 12.4 | 26.6 | .03(.20) | .01 | .05(.33) | .02 | 8.8 | 21.0 | .12(.04) | .23* |
| Lifestyle & Environment | ||||||||||||
| Social determinants of health |
29.0 | 25.4 | 26.4 | 29.7 | .21(.21) | .08 | .18(.34) | .06 | 17.1 | 31.2 | .10(.04) | .19 |
*
p≤.003 (Bonferroni correction) in adjusted analyses including covariates place of birth, survey language, and education
a
In multivariable analyses, outcome variables were treated as continuous. This table dichotomizes the outcome variables (percentages reflect those reporting themselves to be either “extremely” or “moderately” familiar with each term) for ease of interpretation.
b
In multivariable analyses health literacy was treated as a continuous level predictor. This table dichotomizes the health literacy variable for ease of interpretation.