Table 2.
Most significant meta-analysis results.
| Sample 1 | Sample 2 | Meta-analysis | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||||
| Marker | Gene | Position | Alleles | RAF | Info | OR | 95% CI | p | RAF | OR | 95% CI | p | OR | 95% CI | p |
| rs2028211 | BIN1 | 127,901,657 | C/A | 0.1460 | 0.78 | 1.43 | (0.80, 2.53) | 0.22 | 0.1470 | 3.92 | (2.18, 7.07) | 5.4E-06 | 2.33 | (1.55, 3.52) | 5.3E-05 |
| rs7568133 | ZEB2 | 145,204,976 | A/G | 0.4952 | 0.82 | 2.00 | (1.35, 2.98) | 0.00062 | 0.4775 | 2.55 | (1.27, 5.11) | 0.0085 | 2.12 | (1.50, 3.00) | 1.9E-05 |
| rs10169306 | AC023469.1 | 151,926,472 | A/G | 0.0635 | 0.84 | 1.57 | (0.84, 2.95) | 0.16 | 0.0687 | 4.26 | (2.24, 8.11) | 1.0E-05 | 2.56 | (1.63, 4.02) | 4.3E-05 |
| rs58110523 | FMNL2 | 153,292,235 | C/T | 0.0486 | 0.84 | 2.85 | (1.43, 5.66) | 0.0028 | 0.0483 | 3.71 | (1.48, 9.29) | 0.0052 | 3.13 | (1.80, 5.42) | 4.8E-05 |
| rs74762979 | ARL6IP6 | 153,804,898 | G/A | 0.0957 | 0.88 | 1.88 | (1.07, 3.31) | 0.028 | 0.0763 | 5.25 | (2.39, 11.55) | 3.7E-05 | 2.66 | (1.68, 4.22) | 2.9E-05 |
| rs114101795 | ARL6IP6 | 153,825,388 | A/G | 0.0957 | 0.88 | 1.88 | (1.07, 3.30) | 0.028 | 0.0787 | 5.46 | (2.45, 12.13) | 3.2E-05 | 2.68 | (1.69, 4.25) | 2.8E-05 |
| rs79513402 | ARL6IP6 | 153,829,134 | C/T | 0.0957 | 0.88 | 1.88 | (1.07, 3.30) | 0.029 | 0.0774 | 5.29 | (2.40, 11.66) | 3.6E-05 | 2.66 | (1.68, 4.22) | 2.9E-05 |
| rs78089492 | AC092684.1 | 164,826,751 | G/A | 0.0737 | 0.92 | 2.54 | (1.43, 4.52) | 0.0015 | 0.0655 | 2.56 | (1.27, 5.15) | 0.0082 | 2.55 | (1.64, 3.98) | 3.6E-05 |
Gene, gene that contains or is nearest to marker; Alleles, effect/other allele, where the reference is the minor allele in the sample; RAF, reference allele frequency; Info, IMPUTE2 information quality score.