Table 5.
Summary heat map demonstrating effect sizes of group differences comparing adults aged 36+ years with preclinical and prodromal dementia, and prodromal and clinical dementia
| Domain | Outcomes | Preclinical versus prodromal | Prodromal versus clinical |
|---|---|---|---|
| IQ | KBIT-2 verbal raw score | ** | |
| KBIT-2 nonverbal raw score | * | ||
| Memory | PAL first trial memory score | * | * |
| PAL stages completed | ** | ||
| Orientation | * | ||
| Object memory immediate recall | *** | ||
| Object memory delayed recall | *** | ||
| DLD cognitive score | *** | ||
| OMQ total score | *** | *** | |
| Executive function | IED stage 1 errors | * | |
| IED stages completed | * | ||
| Verbal fluency | |||
| Tower of London | * | ||
| BRIEF-A total score | * | ||
| BRIEF-A Behavioral Regulation Index | |||
| BRIEF-A Metacognition Index | * | * | |
| Attention | SRT total correct | ** | |
| SRT mean latency | ** | ||
| SRT latency standard deviation | * | ||
| Motor | Finger-nose pointing | * | |
| NEPSY-II train and car | ** | ||
| NEPSY-II car and motorbike | |||
| Adaptive | Short ABS total score | *** | |
| Short ABS personal self-sufficiency | ** | ||
| Short ABS community self-sufficiency | ** | ||
| Short ABS personal-social responsibility | ** | ||
| DLD social score | ** |
NOTE. ∗η2 > 0.10, †η2 > 0.15, and ‡η2 > 0.20. Group comparisons included age, premorbid ID severity, and multimorbidity as covariates.
Abbreviations: ABS, Adaptive Behavior Scale; BRIEF-A, Behavior Rating Inventory of Executive Function–Adult version; DLD, Dementia Questionnaire for People with Learning Disabilities; ID, intellectual disability; IED, intra-/extra-dimensional set shift; KBIT-2, Kaufmann Brief Intelligence Test 2; OMQ, Observer Memory Questionnaire; NEPSY-II, Developmental NEuroPSYchological Assessment-II; PAL, paired associates learning; SRT, simple reaction time.