Table 3.
Regions showing correlations between LDH/FA and BMI/SBP in T2DM.
| Region names | Voxel size | MNI coordinates (mm) | r value | |
|---|---|---|---|---|
| BMI & LDH | R inferior temporal lobe (fusiform)∗1 | 136 | 48 -26 -22 | 0.542 |
| L inferior temporal lobe (fusiform) | 155 | -52 -20 -28 | 0.592 | |
| R supra-marginal gyrus | 139 | 58 -14 30 | -0.606 | |
| L inferior parietal lobe (fusiform)∗2 | 457 | -46 8 36 | 0.661 | |
| R superior radiation | 75 | 30 0 24 | -0.574 | |
| L semiovale center/post-central gyrus | 157 | -44 -10 42 | 0.573 | |
| BMI & FA | R inferior temporal lobe (fusiform)∗1 | 117 | 50 -24 -28 | 0.571 |
| L inferior & middle temporal lobe | 104 | -68 -34 -18 | 0.641 | |
| L calcarine cortex (V1) | 77 | -2 -88 4 | -0.714 | |
| L inferior parietal lobe∗2 | 338 | -62 6 18 | 0.629 | |
| SBP & LDH | R temporal Pole&1 | 641 | 48 20 -30 | -0.715 |
| R cerebellum_crus1&2 | 112 | 42 -68 -28 | 0.615 | |
| R inferior temporal love | 247 | 48 -40 -20 | 0.646 | |
| B orbitofrontal area&3 | 276 | 12 40 -18 | 0.635 | |
| R inferior Occipital lobe | 171 | 30 -88 -4 | 0.659 | |
| B cingulum bundle&4 | 256 | 6 -24 46 | 0.616 | |
| SBP & FA | R cerebellum_Crus1&2 | 136 | 46 -62 -34 | 0.620 |
| R temporal pole&2 | 343 | 40 22 -34 | -0.664 | |
| B orbitofrontal area&3 | 206 | -2 40 -22 | 0.674 | |
| L parahippocampus | 168 | -20 -44 -8 | 0.670 | |
| Vermis | 110 | 2 -56 2 | -0.669 | |
| L superior radiation | 111 | -26 8 34 | 0.546 | |
| B cingulum bundle&4 | 71 | 6 -26 44 | 0.634 |
BA, brodmann area; V1, primary visual cortex; OR, optic radiations; LDH, local diffusion homogeneity; FA, fractional anisotropy; BMI, body mass index; SBP, systolic blood pressure; UF, uncinate fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; FPUT, the fronto-parietal U-tracts connecting pre-central and post-central gyrus; CST, corticospinal tract; IFO, inferior fronto-occipital fasciculus; sCC, the fibers of splenium of corpus callosum; mCB, medial cingulum bundle; gCC, genu of corpus callosum; FX, fornix; ST, stria terminalis; R, right, L, left; B, bilateral. ∗Overlapping regions associated with BMI as revealed by both LDH and FA. &Overlapping regions associated with SBP as revealed by both LDH and FA. The number behind ∗ or &: the pairing label for each overlapping region that presents the correlation between LDH/FA and BMI, or between LDH/FA and SBP.