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. 2019 Feb 13;9:1912. doi: 10.1038/s41598-018-36802-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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FRONSAC is compatible with other imaging methods. FRONSAC is applied to a turbo spin echo sequence with an echo train length (ETL) of 8 and effective echo times shown above each column. To calculate the actual scan time reductions the ETL is multiplied with the undersampling factor, yielding scan accelerations of 32 and 48 for these images. Experimental FRONSAC images maintain identical contrast to the Cartesian images at each effective echo time. Black space in the images has been cropped for better visualization.