Fig. 6.

Transcript fusions of HAMPs across cancers. a The fusions of HAMPs in TCGA samples are shown in Circos plots. The fused genes are illustrated as lines that connect two parental genes. The intensity of the line corresponds to the tier of the fusion event. b Summary of the HAMP transcript fusions across cancers. The size of the bubble: number of the HAMP transcript fusion events across 33 cancer types. The HAMPs coding in black and gray indicate a gene with fusion events ≥ 10 and < 10, respectively. The phylogenetic trees were generated by multiple sequence alignments of the full-length sequences of the proteins. c Percentage of tumor specimens with HAMP transcription fusion events across all cancer types. d Percentage of tumor specimens with HAMP transcription fusion events in each cancer type