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. 2019 Feb 13;9:1920. doi: 10.1038/s41598-019-38566-y

Figure 3.

Figure 3

Anti-miR-17 but not anti-miR-18, anti-miR-19, or anti-miR-25 reduced cyst progression. (A) Representative H&E-stained kidney sections from Pkd1-KO mice treated anti-miR-17 (a17), anti-miR-18 (a18), anti-miR-19 (a19), or anti-miR-25 (a25) mice are shown. Only mice treated with anti-miR-17 showed reduction in kidney size. (B) Kidney-weight-to-body weight ratios (KW/BW) and (C) cyst index were reduced only in mice treated with anti-miR-17 treated mice compared to PBS. Data are presented as mean ± SEM. Statistical analyses: One-way ANOVA (post hoc analysis: Dunnett’s multiple comparisons test), ns indicates P > 0.05.