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. 2019 Feb 13;9:1997. doi: 10.1038/s41598-018-38289-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Single molecule tracking analysis for RarA-YFP in recombinational and Y-polymerase mutant backgrounds. (A) RarA-mVenus dynamic population difference in the backgrounds studied compared to wild type in no-drug condition. (B) RarA-mVenus DPDs after addition of 0.5 mM H₂O₂, or C) of 50 ng/ml MMC, for 60 min, compared to drug-free conditions in each background. * represent statistical significance in Z-test (included in SMTracker, see methods).