Table S8.

Sensitivity Analyses: Bivariate Statistics for Psychotic Experiences and Dichotomous Tobacco Use Variable (Nonsmokers and Smokers)

	Model	Base	EP	Model fit	Df	AIC	Δ–2LL	Δ df	p
				–2LL
Paranoia	Saturated model		10	15445.00	9993	–4541.00
	ACE	Sat	11	15445.00	9994	–4543.00	0.01	1	.999
	AE (retained C for tobacco)a	ACE	9	15446.78	9996	–4545.22	1.78	2	.411
	ACE dropped rA	ACE	10	15447.58	9995	–4542.42	2.58	1	.108
	ACE dropped rC	ACE	10	15445.17	9995	–4544.83	0.17	1	.682
	ACE dropped rA and rC	ACE	9	15466.39	9996	–4525.61	21.39	2	<.001
	AE dropped rA	ACE	8	15468.29	9997	–4525.71	23.29	3	<.001
Hallucinations	Saturated model		10	15613.03	10001	–4388.97
	ACE	Sat	11	15613.03	10002	–4390.97	0.01	1	.999
	AE (retained C for tobacco)	ACE	9	15621.10	10004	–4386.90	8.07	2	.018
	ACE dropped rA	ACE	10	15614.98	10003	–4391.02	1.95	1	.162
	ACE dropped rCa	ACE	10	15613.04	10003	–4392.96	0.01	1	.929
	ACE dropped rA and rC	ACE	9	15625.36	10004	–4382.64	12.34	2	.002
Cognitive disorganization	Saturated model		10	15583.50	9993	–4402.50
	ACE	Sat	11	15583.62	9994	–4404.38	1.12	1	.733
	AE (retained C for tobacco) a	ACE	9	15583.63	9996	–4408.38	0.01	2	.998
	ACE dropped rA	ACE	10	15589.15	9995	–4400.85	5.53	1	.019
	ACE dropped rC	ACE	10	15583.63	9995	–4406.38	0.01	1	.944
	ACE dropped rA and rC	ACE	9	15615.04	9996	–4376.96	31.42	2	<.001
	AE dropped rA	ACE	8	15615.04	9997	–4378.96	31.42	3	<.001
Negative symptoms	Saturated model		10	14113.87	10003	–5892.13
	ACE a	Sat	11	14113.87	10004	–5894.13	0.01	1	0.999
(parent-rated)	AE (retained C for tobacco)	ACE	9	14144.63	10006	–5867.37	30.76	2	<.001
	ACE dropped rA	ACE	10	14117.12	10005	–5892.88	3.25	1	0.072
	ACE dropped rC	ACE	10	14117.19	10005	–5892.81	3.32	1	0.069
	ACE dropped rA and rC	ACE	9	14162.75	10006	–5849.25	48.88	2	<.001

Note: Saturated models constrained means, thresholds and phenotypic correlations across twin order. Nonsmokers defined as those who had never smoked or who smoked less than 50 lifetime cigarettes. Smokers were those who smoked 50 or more lifetime cigarettes and who smoked in the past year. –2LL = minus 2 log-likelihood; Δdf = difference in degrees of freedom compared to the base model; Δ–2LL=log-likelihood ratio chi-square test comparing the –2LL of each model to the –2LL fit of the base model; A = additive genetic influences; Base = comparison model; AIC = Akaike's Information Criterion (lower values reflect a more parsimonious and therefore preferred fit); C = common environmental influences; df = degrees of freedom; E = unique environmental influences; EP = estimated parameters; r_A = genetic correlation; r_C = common environmental correlation; r_E = unique environmental correlation

^aMost parsimonious model.