Table 1.
Transduction Patterns of AAV Serotypes DJ, DJ8, and PHP.B in the Inner Ear Cells of the Cochlea
| Serotype | Cochlear Cell Type | Cochlear Cell Type with Highest Transduction Rate |
|---|---|---|
| rAAV2/DJ | inner hair cells | inner hair cells |
| outer hair cells | outer hair cells | |
| supporting cells | supporting cells | |
| Reissner’s membrane | Reissner’s membrane | |
| interdental cells | interdental cells | |
| root cells | root cells | |
| rAAV2/DJ8 | inner hair cells | inner hair cells |
| outer hair cells | outer hair cells | |
| supporting cells | ||
| Reissner’s membrane | ||
| root cells | ||
| rAAV2/PHP.B | inner hair cells | inner hair cells |
| outer hair cells | outer hair cells | |
| supporting cells | ||
| Reissner’s membrane |