Table 2.
Treatment Group | Total Cholesterol (mg/dl) | HDL (mg/dl) | LDL (mg/dl) |
---|---|---|---|
Sprague-Dawley | |||
Regular Diet-4 wk | 66.9 ± 2.70 | 29.6 ± 0.90 | 7.5 ± 1.08 |
Regular Diet-12 wk | 64.3 ± 2.24 | 27.3 ± 0.66 | 6.38 ± 1.33 |
Regular Diet-24 wk | 80.3 ± 5.89* | 27.8 ± 0.93 | 11.0 ± 0.59* |
F344 | |||
Regular Diet-4 wk | 63.3 ± 2.40 | 27.9 ± 0.77 | n.d. |
Regular Diet-12 wk | 71.5 ± 3.18# | 28.1 ± 0.52 | n.d. |
Regular Diet-24 wk | 87.3 ± 5.53# | 30.4 ± 1.75 | n.d. |
Brown-Norway | |||
Regular Diet-4 wk | 64.3 ± 1.34 | 23.4 ± 0.25 | 17.0 ± 0.98 |
Regular Diet-12 wk | 65.5 ± 1.77 | 21.1 ± 0.37^ | 15.9 ± 0.78 |
Regular Diet-24 wk | 70.4 ± 1.37 | 24.1 ± 0.41 | 15.1 ± 1.08 |
Note. n.d. = Below limit of detection; values are means ± standard error (n = 8); *Significantly different from corresponding 4 and 12 wk groups for a specific lipid analyte; #Significantly different from 4 wk group for a specific lipid analyte; ^significantly different from 4 and 24 wk for a specific analyte (p < 0.05).