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. 2019 Jan 25;17:177–185. doi: 10.1016/j.csbj.2019.01.007

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© 2019 The Authors. Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig.1 — Schematic presentation of the two-tissue compartment. Cplasma represents the tracer concentration in blood, C1 the unbound (non-metabolized) tracer in tissue, and C2 the metabolized tracer in tissue. In case of FDG k1 is the transport rate of the tracer from blood to tissue, k2 the transport rate back to blood, k3 the phosphorylation rate and k4 the dephosphorylation rate.